在心力衰竭中适度持续或高强度间歇运动与减少喷射分数:缺血和非缺血病因之间的差异
Martin Halle1,2, Eva Prescott3, Emeline M Van Craenenbroeck4,5
1Department of Prevention and Sports Medicine, Technical University of Munich, University hospital ´Klinikum rechts der Isar´, Munich, Germany.
运动强度和类型不会影响心力衰竭的结果,减少喷射率 (HFrEF) 患者,无论原因是缺血还是非缺血心肌病. 这一发现适用于心脏尺寸,功能和运动能力.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 心脏衰竭研究研究
背景情况:
- 建议在心力衰竭和减少喷射率 (HFrEF) 时进行运动.
- 目前的指导方针并没有根据心力衰竭病因区分运动模式或强度.
- 运动强度对不同心力衰竭病因的影响尚不清楚.
研究的目的:
- 研究中度和高强度运动对HFrEF患者心脏功能和运动能力的影响.
- 为了比较患有缺血性心肌病 (ICM) 和非缺血性心肌病 (NICM) 的患者之间的结果.
主要方法:
- 在SMARTEX-HF试验中,231名HFrEF患者参加了为期12周的监督炼计划.
- 患者被随机分配到中等持续训练 (MCT),高强度间歇训练 (HIIIT) 或建议定期炼 (RRE).
- 左心室末端透气直径 (LVEDD),喷射率 (LVEF) 和峰值氧气消耗 (峰值VO2) 在基线,12周和52周被评估.
主要成果:
- 病因学 (ICM与NICM) 在12周或52周后没有影响LVEDD或LVEF的变化.
- 与NICM患者相比,ICM患者的基线和12周峰值VO2较低,但运动训练没有改变这一差异.
- 无论是中度运动还是高强度运动,都没有基于HFrEF病因学的差异性影响.
结论:
- HFrEF的病因不影响对中度或高强度运动的反应.
- 运动干预措施也可以类似地应用于ICM和NICM患者的心脏尺寸,缩功能和运动能力.
- 调查结果支持对HFrEF进行运动的指导方针建议,而不是根据病因学进行具体区分.
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