瑞典儿童患有回避性限制性食物摄入障碍现型的同时存在的精神和体质疾病
Marie-Louis Wronski1,2,3, Ralf Kuja-Halkola1, Elin Hedlund1
1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
medRxiv : the preprint server for health sciences
|April 1, 2024
概括
患有回避性限制性食物摄入障碍 (ARFID) 的儿童患神经发育,胃肠道和呼吸系统疾病的风险明显更高. 这项研究突出了跨儿科专业的ARFID青少年的复杂健康需求.
科学领域:
- 儿科健康 儿科健康
- 饮食障碍 饮食障碍 饮食障碍 饮食障碍
- 伴发病性研究 研究.
背景情况:
- 避免性限制性食物摄入障碍 (ARFID) 影响儿童的身体健康和心理社会功能.
- 有限的大规模研究存在于ARFID并发症.
- 了解ARFID的相关条件对于综合护理至关重要.
研究的目的:
- 系统地调查儿童与ARFID相关的精神和身体状况.
- 描述ARFID患者的综合医疗保健需求.
- 为ARFID在儿科专业的广泛影响提供证据.
主要方法:
- 利用瑞典双胞胎队列在6-12岁儿童中识别ARFID表型.
- 分析了家长报告和注册数据,检查了1000多个精神和体质疾病的ICD代码.
- 计算了90个结果的危险比率 (HR) 和发病率比率 (IRR),比较了ARFID和没有ARFID的儿童.
主要成果:
- 在患有ARFID的儿童中,观察到神经发育 (例如自闭症,智力障碍),胃肠道 (例如GERD),呼吸道和神经系统疾病的相对风险大幅增加.
- 在ARFID儿童中发现明显更高的精神诊断和更长的住院时间.
- 与对照组相比,ARFID儿童的精神疾病早期诊断发生在儿童中;没有注意到性别特异性差异.
结论:
- 焦虑症与广泛的精神和身体状况有关.
- 患有ARFID的年轻人表现出复杂的健康需求,需要多学科儿科的关注.
- 早期发现并发症和管理对于改善ARFID的结果至关重要.
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