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Updated: Jul 14, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
11:31

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

Published on: June 30, 2016

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"多重屏幕识别了一种特定于 Pseudomonas aeruginosa 的小分子,该小分子向外膜蛋白 OprH 并与 LPS 相互作用"

Bradley E Poulsen, Thulasi Warrier, Sulyman Barkho

    bioRxiv : the preprint server for biology
    |April 1, 2024
    PubMed
    概括

    研究人员发现了一种新化合物BRD1401,通过准其外膜来杀死耐药细菌Pseudomonas aeruginosa. 这一发现为打击抗微生物药物耐药性的新方法提供了机会.

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    High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method07:51

    High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method

    Published on: May 21, 2018

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    Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions08:31

    Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

    Published on: December 1, 2020

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    相关概念视频

    Gene Regulation in Microbial Communities: Quorum Sensing01:28

    Gene Regulation in Microbial Communities: Quorum Sensing

    Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...