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Updated: Jun 29, 2025

Aip1p Dynamics Are Altered by the R256H Mutation in Actin
08:57

Aip1p Dynamics Are Altered by the R256H Mutation in Actin

Published on: July 30, 2014

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扩展性心肌病相关的骨肌动蛋白 (ACTA1) 突变R256H破坏了动蛋白的结构和功能,并导致心肌细胞的低收缩性

Ankit Garg1,2,3, Silvia Jansen4, Rui Zhang2

  • 1Division of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD USA.

bioRxiv : the preprint server for biology
|April 1, 2024
PubMed
概括

骨肌动蛋白 (ACTA1) 的特定突变甚至在低水平上也会导致扩张性心肌病 (DCM). 这种R256H突变通过影响活性丝来破坏心肌收缩性.

关键词:
在Actin中的Actin是Actin.生物科学 生物科学生物物理和计算生物学心肌病性心脏病 - 心肌病性心脏病收缩性 收缩性的肌肉 肌肉 肌肉 肌肉 肌肉

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