以前结核病对周产期HIV-1感染青少年心血管状况的影响
medRxiv : the preprint server for health sciences
|April 1, 2024
概括
患有围产期获得的艾滋病毒和结核病史的青少年由于心室动脉合发生变化而导致心脏效率下降,而不是炎症. 需要进一步的研究来了解这些心血管影响.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 儿科 儿科 儿科
背景情况:
- 同时发生的HIV-1感染 (HIV) 和结核病 (TB) 影响心血管健康,特别是在患有围产期HIV (APHIV) 的青少年中.
- 以前活跃的结核病对APHIV心脏效率的具体影响仍未得到充分研究.
结论:
- 以前的结核病对患有周围产期艾滋病毒的青少年的心脏效率产生了负面影响,主要是通过改变心室动脉合.
- 通过hsCRP测量的炎症似乎没有介导这种效应.
- 需要对更广泛的免疫生物标志物进行进一步的研究,以阐明临床意义.
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