相关实验视频

Updated: Jun 29, 2025

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
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Published on: August 9, 2019

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生物冲浪器用于系统地跟踪导致蛋白质异型多样性的调节机制

Mayank Murali1, Jamie Saquing2, Senbao Lu3,4

  • 1Broad Institute of MIT and Harvard University, Cambridge, MA, USA.

bioRxiv : the preprint server for biology
|April 1, 2024
PubMed
概括

生物冲浪器是一种新的计算工具,通过跟踪转录组,拼接和翻译变异来分析蛋白质异型. 它揭示了替代转录起点驱动大多数N-终端变异,而移是C-终端多样性的关键.

关键词:
另一个替代拼接.在GENCODE中,我们可以使用GENCODE.LRS 特别版 特别版转录启动站点 (TIS) 是一个转录启动站点.另一种转录起点 (altTSS)内部保留可以保持.长时间阅读序列排序.无意义媒介衰变 (NMD) 是一种无意义媒介衰变.开放的阅读框架 (ORF)毒物 毒物 毒物 毒物 毒物蛋白质的异构形式.蛋白质序列的蛋白质序列是什么阅读框架转移 阅读框架转移顺序对齐的顺序对齐.转录起始地点 (TSS)转录终端站点 (TSS) 是一个转录终端站点.

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