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Updated: Jun 29, 2025

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
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miRNA电路模块用于精确,可调节的基因表达控制.

Rongrong Du1, Michael J Flynn1, Monique Honsa2

  • 1Howard Hughes Medical Institute and Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

bioRxiv : the preprint server for biology
|April 1, 2024
PubMed
概括

研究人员开发了DIMMERs,一种基于miRNA的合成基因表达调节剂. 这些电路提供精确的,可调节的转基因控制,使研究和治疗的各种细胞类型的蛋白质水平保持一致.

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