人类大脑结构-功能合的空间和时间模式与发展联系在一起.
Guozheng Feng1,2,3, Yiwen Wang1,2,3, Weijie Huang1,2,3
1State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
bioRxiv : the preprint server for biology
|April 1, 2024
概括
脑子 脑子 脑子 脑子
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 认知神经科学 认知神经科学
背景情况:
- 大脑的结构和功能连接对于认知至关重要.
- 结构连接体 (SC) 与功能连接体 (FC) 合之间的发育关系及其对认知和基因表达的影响尚未得到充分理解.
研究的目的:
- 为了研究SC-FC合的发展轨迹.
- 探索SC-FC合,认知能力和转录结构之间的关系.
主要方法:
- 利用了来自439名参与者的多式磁共振成像数据 (年龄为5.7-21.9).
- 通过使用皮质内和皮质外结构连接来预测功能连接,特征化了SC-FC合.
主要成果:
- 在视觉和体力运动网络中,SC-FC合最强,在皮层区域的发育增加.
- SC-FC 合可显著预测通用智能,特别是在前端对联和默认模式网络中.
- 发育性SC-FC合与与小基因相关的基因 (阳性) 和与天体细胞相关的基因 (阴性) 有关.
结论:
- 在开发过程中,SC-FC合经历了异质的成熟.
- SC-FC 合在一般智力的个体差异中起作用.
- 与寡细胞和星球细胞相关的基因表达影响SC-FC合的发展.
更多相关视频
09:01A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
Published on: May 7, 2014
10.2K
17:06Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
Published on: November 8, 2012
26.2K
相关概念视频
01:30Organization of the Brain
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
01:30Neuron Structure
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to cellular...
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to cellular...