在腹腔透析患者中爆发了Burkholderia cepacia复杂出口部位感染,由受污染的喷雾敷料引起
Lily Shui-Kuen Cheng1, Sandy Ka-Yee Chau1, Wai-Shan Chan2
1Department of Pathology, United Christian Hospital, Hong Kong Special Administrative Region.
Infection prevention in practice
|April 1, 2024
概括
污染的喷雾带在腹腔透析患者中引起了Burkholderia cepacia复合体 (BCC) 感染. 移除涉及的喷雾带来了BCC出口部位感染的显著减少,突出了伤口护理中的关键风险.
科学领域:
- 传染性疾病 传染性疾病
- 医学微生物学 医学微生物学
- 公共卫生 公共卫生
背景情况:
- 2020年7月,香港的腹腔透析 (PD) 患者发生了四种Burkholderia cepacia复合体 (BCC) 出口部位感染的集群.
- 这些感染引起了医院感染控制小组的流行病学调查.
研究的目的:
- 在PD患者中调查一组BCC退出部位感染的原因.
- 确定感染源并实施控制措施.
主要方法:
- 从2011年1月到2020年7月,对患有培养确认BCC出口部位感染的PD患者进行了一项回顾性队列研究.
- 流行病学调查包括病例发现,分子类型 (多位序列类型) 和疫情后监测.
主要成果:
- 从2013年开始,BCC出口部位感染的显著增加被观察到,在2015年达到顶峰,并在2020年持续增加.
- 潜在的来源被追溯到2012年12月引入的一批特定的喷雾敷料.
- 从未打开的和正在使用的喷雾敷料容器中分离了BCC,分子类型确定了患者和敷料分离物的遗传相关性.
结论:
- 基于水的喷雾敷料可以作为BCC的储存库,导致伤口感染.
- 污染的喷雾带给患者带来了固有的风险,特别是那些在内置导管附近患有慢性伤口的患者.
- 移除受污染的喷雾敷料导致BCC出口部位感染的持续减少.
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