相关实验视频
Updated: Jun 29, 2025

05:48
Rapid Generation of Amyloid from Native Proteins In vitro
Published on: December 5, 2013
6.2K
系统性粉样蛋白A蛋白粉样蛋白与胃肠道参与
Olubunmi Akharume1, Solabomi Ojeniyi1, Haider A Naqvi1
1Department of Medicine, Medstar Union Memorial Hospital and Medstar Franklin Square Medical Center, Baltimore, MD.
ACG case reports journal
|April 1, 2024
概括
系统性粉样蛋白A蛋白粉样症是注射药物的人的脏并发症. 这一案例突出了罕见的胃肠道出血作为这种疾病的症状.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
背景情况:
- 系统性粉样蛋白A蛋白 (AA) 粉样症主要影响脏,并且在注射药物的人群中经常被忽视.
- 在全身AA粉样性粉症中,胃肠道的参与是不常见的,特别是当与非法药物使用相关时.
研究的目的:
- 报告一个罕见的胃肠道出血病例,该病例发生在一个患有系统性AA氨基粉症和注射药物使用史的患者身上.
- 要突出诊断挑战和胃肠道AA粉样粉症的临床表现在这个人群中.
主要方法:
- 一名40岁男性的病例报告,有注射药物使用史,皮肤感染和脏AA粉样性粉症.
- 临床评价,包括对血和多发性排水的管理.
- 对于复发性血病的胃肠道咨询.
- 胃肠道活检用于组织病理学检查.
主要成果:
- 患者出现了无痛的血性肠道排便 (血症).
- 最初的保守管理提供了暂时的缓解.
- 经常出现的血症促使进一步调查.
- 胃肠道活检证实了粉样蛋白沉积物.
结论:
- 系统性AA氨基化症可能伴有胃肠道出血,即使主要诊断为脏干扰.
- 这一案例强调了在有注射药物使用史的人群中考虑AA粉样粉症的胃肠道表现的重要性.
- 早期识别和活检对于诊断这种不常见的并发症至关重要.
相关概念视频
Gastritis-II: Pathophysiology
324
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
324
Amyloid Fibrils
5.1K
5.1K
Chronic Bowel Disorders: Introduction
450
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
450
Inflammatory Bowel Disease II: Crohn's Disease
233
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
233
Inflammatory Bowel Disease I: Ulcerative Colitis
179
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
179
What is Monogastric Digestion?
71.1K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.1K

