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Updated: Aug 12, 2026

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使用机器学习的TNFRSF19与基于TNF家族的预后模型和质瘤的亚型的关联

Youwei Guo1,2, Quanwei Zhou3, Min Wei2,4

  • 1Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.

Heliyon
|April 1, 2024
PubMed
概括

使用TNF家族成员 (TFM) 的新预后模型准确地预测了质瘤的结果. TNFRSF19的瘤表达表明预后不佳,并影响瘤微环境,建议它作为治疗点.

关键词:
质瘤是一种质瘤.免疫细胞是免疫细胞.预测 预后 预测 预测的亚型 亚型 亚型 亚型这就是TNF TNF.美国TNFRSF19

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The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...