开发和验证一个临床预测模型的早期呼吸机断奶在心脏手术后的心脏手术
Rong-Cheng Xie1, Yu-Ting Wang1, Xue-Feng Lin1
1Department of Critical Care Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen 361015, Fujian province, PR China.
Heliyon
|April 1, 2024
概括
一个新的名图预测心脏手术患者的输出管成功. 该工具可以识别像EuroSCORE II和BNP等风险因素,帮助临床决策,以改善患者的康复.
科学领域:
- 心脏病学 心脏病学
- 关键护理医学 关键护理医学
- 医疗信息学 医疗信息学
背景情况:
- 机械通风断奶是心脏手术后的一个关键挑战.
- 成功的输出管改善了患者的康复和生存率.
- 延迟的输出管和断奶失败是常见的并发症.
研究的目的:
- 开发和验证一个临床预测模型,以在心脏外科手术后的患者中成功进行输出管.
- 创建一个预测性名图,以评估个体的输出管成功概率.
主要方法:
- 使用已识别的风险因素构建了一个预测名录.
- 使用的接收机操作特性 (ROC) 和校准曲线用于模型评估.
- 执行决策曲线分析 (DCA) 来评估临床效用.
主要成果:
- 确定了五个风险因素:男性比例,EuroSCORE II,操作时间,时间,出血和BNP水平.
- 诺莫格拉姆的AUC为0.880 (训练) 和0.753 (验证).
- DCA和临床影响曲线显示出良好的临床效用.
结论:
- 开发的诺米图准确地预测心脏外科手术后患者的输出管成功.
- 该工具有助于个人风险评估和明智的临床决策.
- 预测因素包括EuroSCORE II,持续时间,出血和手术后的BNP水平.
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