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Updated: Jun 29, 2025

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微质细胞在健康和疾病中的蛋白质学景观

Emma Davis1,2, Amy F Lloyd3

  • 1The Francis Crick Institute, London, United Kingdom.

Frontiers in cellular neuroscience
|April 1, 2024
PubMed
概括

微质细胞,大脑的免疫细胞,在神经退行性疾病中至关重要. 蛋白质组学提供了对它们的功能以及在疾病中基因和蛋白质表达之间的联系的更深入的理解.

关键词:
质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量微质细胞中的微质细胞神经退行症的神经退行症神经科学 神经科学蛋白质组学 蛋白质组学

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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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