鱼类发育中的交织过程:微生物群落的继承和免疫成熟
Lisa Zoé Auclert1, Mousumi Sarker Chhanda1,2, Nicolas Derome1
1Département de Biologie, Institut de Biologie Intégrative et des Systèmes, Université Laval, Québec, Canada.
PeerJ
|April 1, 2024
概括
鱼类微生物群在免疫系统的发展和健康中起着至关重要的作用. 了解这种双向沟通是改善鱼类水产养殖和在没有抗生素的情况下预防疾病的关键.
科学领域:
- 水生免疫学 水生免疫学
- 微生物组研究的研究.
- 鱼类健康和疾病
背景情况:
- 鱼类是各种微生物 (微生物群) 的宿主,对生长,免疫力和病原体防御至关重要.
- 目前的水产养殖疾病预防 (疫苗接种,消毒,抗生素) 有缺点,包括压力,成本和抗生素耐药性.
- 鱼类微生物群对宿主发育,健康和生存至关重要,强调需要了解宿主-微生物相互作用.
结论:
- 考虑到微生物群与免疫系统的相互作用,提高了我们对鱼类免疫学的理解.
- 在生命早期对微生物群的耐受性发展支持健康的成年微生物群落.
- 均衡的宿主微生物群相互作用可以防止有害的炎症,并保持免疫和微生物的平衡.
相关概念视频
01:22Development of Immunocompetence
306
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
306
01:07Speciation Rates
21.2K
Overview
21.2K