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塑性主导的进化和突变主导的进化是相同的发育基因调节网络的不同模式

Eden T H Ng¹, Akira R Kinjo¹

¹Department of Mathematics, Universiti Brunei Darussalam, Gadong, Brunei.

|April 1, 2024

概括

进化论得到了调和:塑性驱动的进化 (PLE) 在大环境变化下占主导地位,而突变驱动的进化 (MLE) 在小变化下占主导地位,由发育系统过渡驱动.

科学领域:

进化生物学是进化的生物学.
发育生物学是发展生物学.
系统生物学系统生物学

背景情况:

突变导致的进化 (MLE) 被塑性导致的进化 (PLE) 挑战,在这种过程中,环境变化会诱导适应性表型,这些表型后来被遗传适应.
发育系统通常对环境和突变变化具有强大耐受性,这就提出了适应性可塑性的过渡问题.

研究的目的:

为了研究MLE和PLE之间的进化动态.
探索发育系统的稳健性如何影响进化途径.
用基因调节网络模型调和相互矛盾的进化理论.

主要方法:

构建了一个基因调节网络 (GRN) 模型,集成开发,层次调节和环境线索.
模拟了GRN模型在不同程度的环境变化中的演变.
分析了表型分布和系统对干扰的易感性.

主要成果:

在GRN模型中,在大环境变化下显示PLE,在小环境变化下显示MLE.
该模型显示,随着环境变化大小的增加,从强度过渡到易受性.
在强度崩之前,表型分布变得有偏见,并与环境变化保持一致,从而促进了适应.

结论:

从MLE到PLE的进化过渡是由与环境变化增加的发展转变驱动的,从强状态转变为易感状态.
基因调控网络模型可以整合和调和突变主导的进化和可塑性主导的进化.
发育系统的可塑性是环境压力下的适应性进化的一个关键因素.

关键词:

适应能力适应能力隐秘的遗传变异隐秘的遗传变异发展偏见是指发展偏见.环境变化环境变化这就是EvoDevo.遗传适应性是一种基因适应性.现型性可塑性现型性可塑性坚固性坚固性

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