冠状病毒疫苗接种对患者发作的影响
Memet Sakir Delil1, Bengi Gul Turk1, Esra Kochan-Kizilkilic2
1Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Heliyon
|April 1, 2024
概括
接种COVID-19疫苗对于患者来说是安全的. 无论是mRNA还是非活化疫苗,都没有显著增加发作风险,这支持它们在这个人群中的使用.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 关于COVID-19疫苗在患者的安全性和有效性的数据有限.
- 建立疫苗耐受性和并发症概况对于为患者 (PWE) 制定疫苗接种指南至关重要.
研究的目的:
- 研究两种COVID-19疫苗 (mRNA和无活化) 对患者发作活动的影响.
- 评估患者COVID-19疫苗接种的安全性和耐受性.
主要方法:
- 一项涉及318名进入门诊的患者的研究.
- 通过采访收集的数据包括患者人口统计学,特征,抗药物治疗方案和接种疫苗后的发作频率.
- 患者接受了Pfizer/BioNTech mRNA或Sinovac无活化的COVID-19疫苗.
主要成果:
- 在318名患者中,19名患者在接种疫苗后报告了发作频率增加 (17名使用mRNA,2名使用非活化疫苗).
- 疫苗接种和发作频率增加,年龄,持续时间,发作类型或诱导之间没有发现显著的关系.
- 没有报告任何状态的病例.
结论:
- 用mRNA和非活化疫苗接种COVID-19疫苗似乎是安全的,并且在患者中耐受良好.
- 这项研究提供了证据来支持医生向患者推COVID-19疫苗.
- 进一步的研究可以加强在这个患者群体中针对COVID-19疫苗接种指南的建议.
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