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夜班工作与成年人骨质疏松症风险之间的关联:使用NHANES进行横截面分析
Yu Qian1,2, Jianchun Mao1,2
1Shanghai University of Traditional Chinese Medicine, NO.1200 Cai Lun Road, Pudong New District, Shanghai, 201203, People's Republic of China.
夜班工作与美国成年人患骨质疏松症的风险更高有关. 这种风险因年龄,性别和不健康的生活方式选择而增大,特别是在老年女性中.
科学领域:
- 职业健康 职业健康 职业健康
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 夜班工作在全球普遍存在,影响着数百万工人.
- 骨质疏松症是一个重大的公共卫生挑战,增加骨折风险.
- 职业暴露和慢性疾病风险之间的相互作用需要进一步研究.
研究的目的:
- 确定夜班工作是否会增加美国成年人骨质疏松症的风险.
- 探索年龄,性别和生活方式因素如何改变这种关联.
- 分析夜班工作对骨矿物质密度 (BMD) 和骨质疏松症患病率的影响.
主要方法:
- 使用国家健康和营养检查调查 (NHANES) 数据 (2007-2020) 的横截面研究.
- 包括4408名美国成年人 (20-80岁);分析了工作时间表,生活方式和BMD.
- 使用线性和逻辑回归,按性别和年龄分层 (≥50岁).
主要成果:
- 夜班工作与50岁以上妇女的脊柱T-分数下降相关.
- 骨质疏松症的患病率增加与总人口 (OR=2.31) 和女性≥50 (OR=4.6) 的夜班工作有关.
- 多变量调整考虑了年龄,性别和生活方式因素.
结论:
- 夜班工作与美国成年人患骨质疏松症的风险更高有关.
- 年龄,性别和生活方式的综合影响显著影响这种风险.
- 针对夜班工作者,特别是老年妇女,可能需要有针对性的干预措施.
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