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相关概念视频

Gross Anatomy of the Lungs01:17

Gross Anatomy of the Lungs

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The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
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Anatomy of Respiratory System II: Lower Respiratory Tract01:31

Anatomy of Respiratory System II: Lower Respiratory Tract

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The lower respiratory tract is anatomically composed of several vital structures, including the larynx, trachea, bronchial tree, alveoli, lungs, and pleurae. Each component has a specific function, and all are intricately connected to ensure efficient respiration.
The Larynx
It is located between the pharynx and the trachea, acts as a passageway for air, and hosts several critical structures, such as the epiglottis, vocal cords, and glottis. The epiglottis acts as a gateway, guiding food to the...
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Pneumonia I: Introduction01:30

Pneumonia I: Introduction

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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The Respiratory System01:16

The Respiratory System

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The respiratory system is comprised of the organs that enable breathing. Air enters the nostrils and mouth, followed by the pharynx (throat) and larynx (voice box), which lead to the trachea (windpipe). In the thoracic cavity, the trachea splits into two bronchi that allow air to enter the lungs. The bronchi split into progressively smaller bronchioles and terminate in small groups of tiny sacs in the lungs called alveoli, where gas exchange occurs.
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Pleura of the Lungs01:13

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Updated: Jun 29, 2025

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
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Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

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肺部微生物组 肺部微生物组

Jay H Lipinksi1, Piyush Ranjan1,2, Robert P Dickson1,2,3

  • 1Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, MI.

Journal of immunology (Baltimore, Md. : 1950)
|April 1, 2024
PubMed
概括
此摘要是机器生成的。

肺部微生物群,曾经被认为是无菌的,现在是充满活力的微生物群落. 这些社区的变化与肺部疾病有关,可以预测结果,提供新的治疗点.

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Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
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Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
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科学领域:

  • 微生物学 微生物学
  • 肺部病理学 肺部病理学
  • 免疫学 免疫学 免疫学

背景情况:

  • 肺部在历史上被认为是无菌的.
  • 测序的进步揭示了呼吸道中低生物量微生物群落,即使在健康个体中也是如此.
  • 这些肺部微生物群落在各种肺部疾病中发生变化.

研究的目的:

  • 审查对呼吸道和帕伦基马肺部疾病中宿主微生物群相互作用的新见解.
  • 探索新陈代谢活跃的微生物及其副产品在肺部疾病发病过程中的作用.
  • 在肺免疫生物学中讨论肠道,口和肺微生物群之间的相互作用.

主要方法:

  • 关于肺微生物组的最新科学文献的综述.
  • 对测序技术在研究呼吸道微生物群方面的进步进行分析.
  • 探索宿主微生物群相互作用及其与肺部疾病的关联.

主要成果:

  • 肺部微生物组的组成,多样性和负担在肺部疾病中发生变化.
  • 这些变化与宿主生理学,免疫力和临床结果相关.
  • 代谢活跃的微生物及其免疫调节副产品与肺部疾病有关.

结论:

  • 了解肺部微生物组为急性和慢性肺部疾病提供了潜在的疾病点.
  • 对宿主微生物群相互作用的了解对于理解肺病的发病过程至关重要.
  • 从研究肺微生物组及其相互作用中,可能会出现新的治疗策略.