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在多发性骨髓瘤患者中,CYP2C19多态性对基于博特佐米布的治疗反应的影响

Lavisha Goel1, Pooja Gupta1, Lalit Kumar2

  • 1Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, 110029, India.

The American journal of the medical sciences
|April 1, 2024
PubMed
概括

在多发性骨髓瘤患者中,CYP2C19遗传变异会影响博特佐米布的有效性. 了解这些遗传差异可以个性化治疗,并可能减少外围神经病变等副作用.

关键词:
博尔特佐米比 (Bortezomib) 是一种可怕的药物.在CYP2C19的多态化中.多发性骨髓瘤是一种多发性骨髓瘤.周围神经病变是一种神经病变.对治疗的反应反应.

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