血造细胞移植后重返工作:幸存者的观点
Rachel B Salit1, Stephanie J Lee1, Neel S Bhatt2
1Fred Hutchinson Cancer Center, Clinical Research Division, Seattle, Washington; Division of Hematology/Oncology, University of Washington Medical Center, Seattle, Washington.
Transplantation and cellular therapy
|April 1, 2024
概括
血造细胞移植 (HCT) 幸存者面临着重返工作 (RTW) 的挑战. 全基性HCT和雇主支持显著影响RTW的成功,大多数幸存者希望更多的移植中心协助.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 移植医学 移植医学
背景情况:
- 血造细胞移植 (HCT) 不仅旨在治愈疾病,而且还旨在恢复患者的生活质量.
- 恢复工作 (RTW) 是许多幸存者的HCT后生活质量的关键方面.
- 了解RTW的促进者和障碍物对于全面的幸存者护理至关重要.
研究的目的:
- 评估HCT幸存者对RTW的促进者和障碍者的观点.
- 评估幸存者对RTW支持干预措施的兴趣.
- 确定影响成功的HCT后RTW的因素.
主要方法:
- 对年龄在18-65岁之间的1至5年后HCT幸存者 (n=994) 进行了一项调查.
- 该调查包括36个问题,来自全国癌症幸存者调查,重点是RTW.
- 344名幸存者完成了调查,其中272人以前有工作史.
主要成果:
- 相比于自身的HCT,异性HCT与当前就业的可能性降低有关.
- 频繁的雇主沟通和支持的雇主与RTW的更高机会相关.
- 45%的工作幸存者报告了工作的修改 (例如,灵活的工作时间,远程工作).
结论:
- 大多数HCT幸存者 (95%) 可以从RTW支持中受益,但只有13%获得了.
- 要求的支持包括对RTW挑战的教育,残疾福利和物理治疗.
- 提供者应主动解决工作状况,障碍,并提供雇主支持的RTW干预措施,特别是对全基性HCT接受者.
相关概念视频
01:22Bone Marrow Sampling and Transplants
328
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
328
01:21Stem Cell Therapy for Tissue Regeneration
4.0K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.0K
01:24Tissue Transplantation
366
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
366
01:01Regulation of Hematopoietic Stem Cells
3.2K
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
3.2K
01:19Multipotency of Hematopoietic Stem Cells
3.1K
The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
3.1K
01:40Cell-mediated Immune Responses
68.2K
Overview
68.2K