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相关概念视频

Knee Joint01:23

Knee Joint

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The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
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Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

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Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
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Ankle Joint01:10

Ankle Joint

1.6K
The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
1.6K
Bones of the Lower Limb: Femur and Patella01:16

Bones of the Lower Limb: Femur and Patella

2.5K
The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Bones of the Upper Limb: Radius01:09

Bones of the Upper Limb: Radius

2.2K
The radius is longer of the two bones that make up the human antebrachium or forearm. At the proximal end, the radius articulates with the capitulum of the humerus and the radial notch of the ulna to form the elbow joint. At the distal end, the radius articulates with the ulna via the ulnar notch, forming the distal radioulnar joint. Distally, the radius also attaches to the carpal wrist bones (scaphoid and lunate) to form the radiocarpal joint.
The radius has a nail-shaped head, and a...
2.2K

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相关实验视频

Updated: Jun 29, 2025

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
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Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

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在骨关节炎中,骨整体接收.

Dinglong Yang1, Jiawen Xu2, Ke Xu1

  • 1Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.

Bone research
|April 1, 2024
PubMed
概括

骨内感,身体对骨状况的感觉,通过影响骨重塑和炎症,在骨关节炎 (OA) 中发挥着关键作用. 针对这种机制可能会提供新的OA治疗策略.

科学领域:

  • 生理学 生理学 生理学
  • 病理学 病理学 病理学
  • 生物医学工程 生物医学工程

背景情况:

  • 内接会调节生理条件和代谢平衡.
  • 骨整体受体特别影响骨代谢的恒常性.
  • 骨关节炎 (OA) 涉及到软骨,底骨和突关节的变化.

研究的目的:

  • 为了提供整体感应和骨整体感应的概述.
  • 为了检查OA中亚带骨微环境和异常重塑.
  • 讨论骨整体受体在骨关节炎发病过程中的作用和潜在的治疗点.

主要方法:

  • 关于整体受理和骨关节炎的文献综述.
  • 分析骨整体受体在子冠状腺骨重塑中的作用.
  • 探索骨性整体受体与OA中的突性炎症的联系.

主要成果:

  • 由骨架整体感受介导的异常机械负荷有助于OA的病理性亚冠骨重塑和硬化.
  • 骨互感受被认为是OA慢性突炎的潜在机制.
  • 脑下骨重塑是OA中对动态关节负荷的关键适应.

结论:

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  • 骨整接是一个关键因素,在异常的底骨头骨改造和膜炎症观察到骨关节炎.
  • 了解骨整体感受为骨关节炎提供了新的治疗途径.
  • 需要进一步的研究来探索针对骨整体受体治疗的挑战和前景.