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Updated: Jun 29, 2025

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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非传统的人类CD61与CD103的配对促进TCR信号传递和抗原特异性T细胞细胞毒性

Megat H B A Hamid1, Pablo F Cespedes1,2, Chen Jin1,3

  • 1CAMS Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Nature immunology
|April 1, 2024
PubMed
概括

研究人员发现CD61是一种蛋白质,在T细胞上与CD103暂时表达,增强了抗瘤免疫力. 这一发现为改善癌症免疫疗法和患者治疗结果提供了一个新的治疗目标.

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