在有恶性病的败血症患者中确定死亡率的预测因素:回顾性队列研究
Leonard Nainggolan1, Rido Prama Eled, Ikhwan Rinaldi
1Division of Tropical and Infection Disease, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia. lenard.goland@yahoo.com.
Acta medica Indonesiana
|April 2, 2024
概括
癌症患者的败血症的死亡率很高. 顺序性器官衰竭评估 (SOFA) 评分和东部合作性瘤组 (ECOG) 绩效状况是影响这些关键病例生存的关键因素.
科学领域:
- 在瘤学瘤学.
- 临界护理医学 临界护理医学
- 流行病学 流行病学
背景情况:
- 败血症具有显著的死亡风险,特别是在患有恶性瘤的患者中.
- 与非癌症患者相比,败血症的癌症患者面临的死亡风险是癌症患者的2.32倍.
- 鉴定恶性瘤性败血症死亡率预测因子对于有效治疗至关重要.
研究的目的:
- 确定影响败血症患者恶性瘤死亡率的因素.
- 为有针对性的治疗策略提供见解.
主要方法:
- 恶性瘤败血症患者的回顾性队列研究 (2020-2022年).
- 使用了来自Cipto Mangunkusumo医院的医疗记录.
- 对相关变量进行了双变量和逻辑回归分析.
主要成果:
- 在350名符合条件的受试者中,观察到82%的死亡率.
- 序列性器官衰竭评估 (SOFA) 评分显示与死亡率有显著的关联 (aOR 5.833).
- 东部合作性瘤学集团 (ECOG) 的绩效状况也与死亡率有显著联系 (aOR 3.490).
结论:
- SOFA评分是癌症败血症患者死亡率的重要预测指标.
- ECOG表现状态是癌症败血症患者死亡率的重要预测因素.
- 这些发现有助于对患有败血症的重症癌症患者的风险分层和管理.
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