在生命的第一年中,狗类结质瘤:5例病例
Esdras C Dos Santos1, Brian A Summers2, Jessica A Elbert1
1Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
概括
狗质瘤在12个月以下的小狗中很罕见. 这项研究详细介绍了五例病例,发现这些年轻狗的质瘤与老狗的质瘤有相似之处.
科学领域:
- 兽医神经学 兽医神经学
- 比較瘤學 的相關搜尋
- 狗类病理学 狗类病理学
背景情况:
- 狗质瘤通常在成年和老年狗中被诊断出来.
- 12个月以下小狗的结质瘤在兽医文献中是非常罕见的.
研究的目的:
- 描述12个月以下的狗中质瘤的发生和特征.
- 为了比较年轻狗的犬类质瘤的临床,形态和免疫组织化学特征与老狗的特征.
主要方法:
- 对5只被诊断患有质瘤的3-12个月龄的狗进行了案例系列审查.
- 瘤组织的组织病理学和免疫组织化学 (IHC) 分析.
- 总体发现与临床症状的相关性.
主要成果:
- 在3-12个月龄的狗中发现了5例犬类质瘤.
- 临床症状包括昏暗,发作,前体征和聋.
- 组织学分类揭示了星系细胞瘤 (3例) 和寡质细胞瘤 (2例).
- 新生体位于脑膜或作为膜结体.
结论:
- 狗质瘤可以发生在生命的第一年,虽然很少见.
- 年轻狗的结质瘤与成年和老犬的结质瘤具有临床,形态和免疫组织化学的相似之处.
- 这项研究扩大了对幼犬患者质瘤呈现的理解.
相关概念视频
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Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
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Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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