群体免疫对特有病:历史概念和对公共卫生政策的影响
David Robertson1, George Heriot2, Euzebiusz Jamrozik3
1Swiss National Science Foundation; Faculty of History, Oxford Centre for the History of Science, Medicine, and Technology, University of Oxford, Oxford, UK.
Journal of evaluation in clinical practice
|April 2, 2024
概括
群体免疫是一个复杂的概念,有各种各样的历史解释. 了解其在特有平衡中的作用,而不仅仅是消除值,对于管理像SARS-CoV-2这样的呼吸道病原体至关重要.
科学领域:
- 免疫学 免疫学 免疫学
- 传染病流行病学 传染病流行病学
- 公共卫生 公共卫生
背景情况:
- "群体免疫"一词在COVID-19大流行期间引起了争议.
- 从历史上看",群体免疫"有多种含义,包括疾病消除门和特有平衡.
- 对于某些疾病,群体免疫力有助于实现动态平衡,而不是根除.
研究的目的:
- 在COVID-19大流行期间分析"群体免疫"的模两可.
- 重新评估和采用群体免疫的历史解释.
- 了解群体免疫在与突变的呼吸道病原体的特有平衡中的作用.
主要方法:
- 从1920年到2022年的学术文学进行了全面的审查.
- 历史和哲学分析的应用.
- 识别和开发相关的群体免疫概念.
主要成果:
- 这项研究强调了围绕群体免疫的概念模两可.
- 长期以来,人们一直认为群体免疫是特有平衡的一个因素.
- 这种解释考虑了宿主种群和突变的呼吸道病毒之间的动态相互作用.
结论:
- 恢复对群体免疫的历史理解至关重要.
- 这种观点有助于控制SARS-CoV-2和其他季节性呼吸道病原体.
- 它提供了对公共卫生干预措施对病原体动态的影响的见解.
相关概念视频
Vaccinations
44.5K
Overview
44.5K
Active versus Passive Immunity
639
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
Active Immunity
Active immunity refers to the resistance one develops...
639
Immunological Memory
605
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
605
Cross-reactivity
31.1K
Overview
31.1K
Infection
7.9K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.9K
Principles of Disease Surveillance
94
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
94


