全球疫苗接种覆盖率和儿童存活率估计:1990-2019年
Haijun Zhang1, Bryan Patenaude2, Haonan Zhang1
1Department of Health Policy and Management, School of Public Health, Peking University, Beijing, China.
Bulletin of the World Health Organization
|April 2, 2024
概括
常规接种疫苗可以显著降低儿童死亡率,避免全球数百万人死亡. 增加对疫苗接种计划的投资至关重要,特别是在Gavi支持的国家,以维持这些拯救生命的努力.
科学领域:
- 全球健康 全球健康
- 免疫学 免疫学 免疫学
- 人口统计学 人口统计学
背景情况:
- 儿童死亡率仍然是一个重大的全球卫生挑战.
- 常规免疫接种是全世界儿童生存策略的基石.
研究的目的:
- 量化例行免疫覆盖率与儿童死亡率降低之间的关联.
- 估计1990年至2019年期间,全球范围内通过特定疫苗避免的死亡人数.
主要方法:
- 利用了来自全球疾病负担研究的儿童死亡率和疫苗覆盖率数据.
- 采用修改后的儿童生存框架和混合效应回归模型.
- 从1990年到2019年,分析了204个国家和地区的数据.
主要成果:
- 常规免疫接种,特别是白喉 - 结节炎 - 百日咳 (DTP),麻疹,轮状病毒和*Haemophilus influenzae*b型疫苗,在全球范围内预防了估计869万名5岁以下儿童的死亡.
- 这意味着儿童死亡率相对于没有疫苗的情况减少了24.2%.
- 这些避免死亡的大多数 (84.2%) 发生在Gavi支持的73个国家,突出显示了全球疫苗接种倡议的影响.
结论:
- 疫苗是一种非常有效的干预措施,可以减少儿童死亡率.
- 持续投资常规免疫计划对于维持和扩大这些收益至关重要.
- 由于疫苗接种努力,Gavi支持的国家的儿童死亡率大幅降低.
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