疟疾载体存活率,传染性和昆虫杀虫剂处理净使用之间的关系在肯尼亚西部
Lucy Abel1, Emma Kimachas1, Evans Omollo2
1AMPATH.
Research square
|April 2, 2024
概括
疟疾载体,如Anopheles蚊子,尽管使用杀虫剂处理网 (ITN),但仍然会感染Plasmodium falciparum. 虫的生存没有受到ITN的影响,而虫的生存只有在ITN覆盖率非常高时才会下降.
科学领域:
- 昆虫学 昆虫学是一门学科.
- 公共卫生 公共卫生
- 疟疾学 疟疾学
背景情况:
- 撒哈拉以南非洲地区的疟疾传播持续,尽管有控制工作.
- 感染后10-14天的Anopheles蚊子存活对于Plasmodium寄生虫的发展和疾病传播至关重要.
研究的目的:
- 评估影响野生捕获的Anopheles蚊子生存的因素.
- 为了确定与Plasmodium falciparum的Anopheles感染相关的因素.
主要方法:
- 在75个家庭的纵向研究,Bungoma县,肯尼亚 (755名参与者).
- 每月通过吸入收集室内成年蚊子.
- 蚊子养7天以确定每日死亡率;形态和分子识别 (Anopheles gambiae复合物);PCR检测腹部中的菌菌.
主要成果:
- 在25个月的时间里,收集了12843只Culex和712只Anopheles蚊子.
- 61.2%的Anopheles存活了7天,死亡率最低的是第5天.
- 测试的Anopheles (683) 中,7.8%为P. falciparum阳性;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. falciparum;An. funestus (10%) 的患病率高于An. 冈比亚特别公司 (6.0%).
- 一个.一个.一个. funestus生存率没有受到杀虫剂处理网 (ITN) 覆盖的影响; An. gambiae s.s.生存率只有在>95%的ITN覆盖率下降.
结论:
- 尽管使用ITN,但Anopheles蚊子继续获得血和P. falciparum感染.
- 虫物种的生存率不同,与家庭高ITN暴露率相反相关.
- 蚊子的卵囊发育不受ITN暴露的影响.
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