认知功能的主观和客观测量在COVID-19后患者中相关:随机对照试验的二次分析
medRxiv : the preprint server for health sciences
|April 2, 2024
概括
后COVID-19条件 (PCC) 中的认知功能显示了患者报告的症状和客观测试结果之间的显著相关性. 这一发现支持使用患者报告的措施来评估PCC患者的认知能力.
科学领域:
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
- 传染性疾病 传染性疾病
背景情况:
- 在后COVID-19条件 (PCC) 中主观和客观认知评估之间的关系在很大程度上仍未被探索.
- 了解这种相关性对于机理性见解和PCC认知缺陷的临床管理至关重要.
研究的目的:
- 研究PCC患者认知功能的主观和客观测量之间的关联.
- 为了确定患者报告的认知缺陷是否与标准化认知测试的表现一致.
主要方法:
- 从一个随机,双盲,安慰剂对照试验中对基线数据进行后期分析,该试验涉及PCC患者.
- 使用感知缺陷问卷 (PDQ-20) 评估主观认知.
- 使用数字符号替换测试 (DSST) 和Trails Making Test (TMT) -A/B. 用于测量客观认知.
主要成果:
- 总共有150名参与者的数据被分析为自我报告的措施和147个联合DSST.
- 在对共变量进行调整后,PDQ-20得分与纸笔DSST和TMT-B得分有显著的相关性.
- 在PDQ-20和TMT-A得分之间没有发现显著的相关性.
结论:
- 在经历PCC的个体中,主观和客观的认知功能的测量之间存在统计学上显著的相关性.
- 临床医生应该考虑一种基于测量的方法,可能优先考虑患者报告的结果,以评估PCC的认知投诉.
相关概念视频
01:30Negative and Cognitive Symptoms of Schizophrenia
48
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
48
01:30Cognitive Development During Adulthood
96
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
96
01:23Assessment of the Cardiovascular System I: Subjective Data
323
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
323
02:20Correlations
32.8K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
32.8K