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Updated: Jun 29, 2025

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CHAI:通过类似矩阵集成进行共识聚类,用于细胞类型识别

Musaddiq K Lodi1, Muzammil Lodi2, Kezie Osei3

  • 1Integrative Life Sciences, Virginia Commonwealth University, Richmond, VA 23284.

bioRxiv : the preprint server for biology
|April 2, 2024
PubMed
概括

CHAI (Consensus Clustering tThrough similArIty matrix integrationIon) 是一种新的工具,它结合了多种聚类方法,以改善单细胞RNA测序 (scRNAseq) 数据中的细胞类型识别.

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
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