乳腺癌免疫治疗的知识映射:从2013年到2022年的文献分析分析
Fanli Qu1,2, Guanwen Wang1,2, Ping Wen3
1Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, China.
Human vaccines & immunotherapeutics
|April 2, 2024
概括
乳腺癌的免疫疗法是一个快速发展的领域. 研究突出了瘤微环境和免疫检查点等关键领域,显示出全球显著的兴趣和临床潜力.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 图书统计学 图书统计学
背景情况:
- 乳腺癌仍然是全球女性癌症死亡的主要原因.
- 免疫疗法代表了癌症治疗的重大进步.
研究的目的:
- 从2013年到2022年,对乳腺癌研究中的免疫疗法进行文献分析.
- 确定当前的研究状况,趋势和该领域的热点.
主要方法:
- 从科学网络核心集合中对7975篇出版物的图书法分析.
- 使用了并发分析 (VOSviewer),并发引用分析 (CiteSpace) 和主题演变 (bibliometrix包).
- 分析包括关键词趋势,国家/机构/作者贡献和合作.
主要成果:
- 确定了六个主要的研究集群:瘤微环境,预后生物标志物,免疫检查点,新药输送,免疫细胞和治疗方法.
- 主要关键词:瘤微环境,三阴性乳腺癌,编程细胞死亡连接体1.
- 美国是最富有生产力的国家,德克萨斯大学MD安德森癌症中心是主要机构,Sherene Loi是最多产的作家.
结论:
- 乳腺癌免疫疗法研究在全球范围内迅速增长.
- 这一领域正越来越受到国际研究人员和机构的关注.
- 免疫疗法具有显著的临床价值和潜在的乳腺癌治疗.
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