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Updated: Jun 29, 2025

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
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干白素-1受体辅助蛋白质阻塞限制了动脉样硬化发展,并减少了斑块炎症

Megan Mulholland1, Marie A C Depuydt2, Gabriel Jakobsson3

  • 1Department of Clinical Sciences, Cardiovascular Research-Immune Regulation, Lund University, Malmö, Sweden.

Cardiovascular research
|April 2, 2024
PubMed
概括

在小鼠中阻断介质素-1受体辅助蛋白 (IL1RAP) 降低了动脉样硬化斑块大小和炎症. 这种方法可能会限制化学激素的产生,为心血管疾病提供新的治疗策略.

关键词:
动脉样硬化是一种动脉样硬化.一个IL-1的IL-1.这就是IL1RAPP.免疫调节是一种免疫调节.炎症 炎症是一种炎症.

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