年轻成人特征与血压轨迹之间的关联
Jaejin An1,2, Heidi Fischer1, Liang Ni1
1Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USA.
Journal of the American Heart Association
|April 2, 2024
概括
肥胖,吸烟和糖尿病等高血压风险因素与年轻人的血压轨迹有关. 肥胖与血压轨迹最高的群体的关联最强.
科学领域:
- 心血管健康 心血管健康
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 从年轻成人到中年,血压 (BP) 轨迹与心血管疾病风险有关.
- 在生命早期了解高血压风险因素对于长期心血管健康至关重要.
- 这项研究调查了高血压风险因素和高血压轨迹在一个大,多样化的人口之间的关联.
研究的目的:
- 为了确定年轻成年人的明显的10年血压轨迹.
- 检查基线高血压风险因素与这些BP轨迹之间的关联.
主要方法:
- 对一大批年轻成年人 (18-39岁) 的大量数据集 (N=355,324) 的分析,未经治疗的血压<140/90 mmHg).
- 利用潜增长曲线建模来定义5个不同的缩BP轨迹.
- 评估了基线特征和确定BP轨迹之间的关联.
主要成果:
- 确定了五种不同的缩血压轨迹,主要由基线血压决定.
- 年龄较大,男性性别,超重,肥胖,目前吸烟,糖尿病前期,糖尿病和高LDL胆固醇与更高的血压轨迹有关.
- 肥胖 (BMI ≥30) 与血压轨迹最高的组 (组5) 显示出最强的关联.
结论:
- 传统的高血压危险因素,包括吸烟,糖尿病和血脂升高,与年轻成年人的血压轨迹有关.
- 肥胖是最高血压轨迹的重要预测因素,强调其在心血管风险发展中的关键作用.
- 早期识别和管理这些风险因素对于预防长期心血管并发症至关重要.
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