在被诊断患有阻塞性睡眠呼吸暂停的年轻患者中,心血管风险
Ida E Albertsen1, Jesper Bille2, Gregory Piazza3
1Department of Otolaryngology Head and Neck Surgery and Audiology Aalborg University Hospital Aalborg Denmark.
Journal of the American Heart Association
|April 2, 2024
概括
患有阻塞性睡眠呼吸暂停 (OSA) 的年轻人面临心血管事件的风险几乎翻了一番. 早期风险分层和预防策略对于管理OSA患者和预防疾病进展至关重要.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与老年人的心血管问题有关.
- 在年轻人群体中,与OSA相关的心血管风险仍然不清楚.
- 这项研究调查了年轻OSA患者的心血管事件事件.
研究的目的:
- 估计被诊断患有阻塞性睡眠呼吸暂停 (OSA) 的年轻患者发生发生性心血管事件的风险.
- 评估50岁或更年轻的个体中OSA和随后的心血管疾病之间的关联.
主要方法:
- 一个全国性的丹麦卫生登记处链接被用来识别一个年龄 ≤50岁的OSA (2010-2018) 患者队列.
- 一个没有OSA的对照组与1:5的比率相匹配.
- 心血管事件 (高血压,糖尿病,心房动,缺血性心脏病,中风,心力衰竭,静脉血栓塞栓症) 和全因死亡率在5年的随访期间被跟踪.
主要成果:
- 该研究包括20,240名年轻OSA患者和80,314名对照.
- 5年后,31.8%的OSA患者经历了心血管事件,而对照组为16.5% (RR, 1.96).
- 与对照组相比,OSA患者的特定风险包括发生高血压 (RR,1.84) 和发生糖尿病 (RR,5.05).
结论:
- 患有OSA的年轻人表现出心血管事件的风险增加,反映了老年人群的发现.
- 建议对年轻的OSA患者采取积极的风险分层和预防措施.
- 这些策略旨在减轻心血管疾病的进展,风险因素的积累和死亡率.
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