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Updated: Jun 29, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

Published on: December 1, 2020

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MolProphet:一种一站式,通用和基于人工智能的平台,用于药物发现的早期阶段

Keda Yang1, Zewen Xie2, Zhen Li2

  • 1Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, P. R. China.

Journal of chemical information and modeling
|April 2, 2024
PubMed
概括

MolProphet是一个用户友好的平台,利用人工智能 (AI) 进行早期的小分子药物发现. 它为目标预测,命中发现和领先优化提供了可访问的工具,为研究人员简化了复杂的AI应用程序.

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Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
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Prodrugs help overcome...
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