心血管指数与中国人群中亚临床左心室功能的高血压特异关联:丹阳研究
Xue Zhang1, Yibo Li1, Xinyue Wang1
1Department of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Journal of clinical hypertension (Greenwich, Conn.)
|April 2, 2024
概括
心血管指数 (CAVI) 与较差的透静心脏功能有关. 这种关联在高血压患者的亚临床缩功能障碍中更为明显.
科学领域:
- 心血管研究的心血管研究.
- 血管健康 血管健康
- 高血压管理 高血压管理
背景情况:
- 亚临床心脏功能障碍是明显心力衰竭的前体.
- 心血管指数 (CAVI) 是衡量动脉硬性的指标.
- CAVI和亚临床心脏功能障碍之间的关系,特别是在高血压患者中,需要进一步阐明.
研究的目的:
- 调查CAVI和亚临床心脏功能障碍之间的关联.
- 为了比较高血压患者与正常血压患者的这些关联.
主要方法:
- 来自丹阳的1887名受试者被录取 (2018-2019).
- 使用VaSera VS-1500A设备测量了CAVI.
- 心声扫描评估了喷射分数 (EF),E/A,心肌环状早期透析速度 (e') 和左心室 (LV) 全球纵向应变 (GLS).
主要成果:
- 较高的CAVI三位数与增加的LV质量指数和E/e'相关,并降低了GLS,E/A和e'速度 (P < .001).
- 经过调整后的分析证实GLS,E/A和e'的降低,同时增加了CAVI三位数 (P ≤ .04).
- 在高血压患者中,增加的CAVI与亚临床LV静脉缩功能障碍的风险更高相关 (OR = 2.61;P = .005).
结论:
- 升高的CAVI与亚临床扩张功能受损有关.
- CAVI和亚临床缩功能障碍之间的联系在高血压患者中更为显著.
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