青少年贝塞特病的眼部表现:来自AIDA网络的基于注册表的分析
Carla Gaggiano1, Abdurrahman Tufan2, Silvana Guerriero3
1Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Policlinico "Le Scotte", Viale Bracci 16, 53100, Siena, Italy.
Ophthalmology and therapy
|April 2, 2024
概括
年轻的贝赫塞特
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 遗传学 是一个遗传学.
背景情况:
- 青少年贝塞特病 (jBD) 是一种罕见的炎症性疾病.
- 眼部干扰是JBD的一个重大问题,可能导致视力丧失.
研究的目的:
- 描述青少年贝塞特病的眼部表现.
- 确定与眼部参与和jBD视觉结果相关的因素.
主要方法:
- 一个基于注册表的观察前性研究.
- 从AIDA网络BD注册表中包括患有jBD和眼部表现的受试者.
- 收集有关人口统计,眼部发现,治疗和视力敏度的数据.
主要成果:
- 尿道炎是最常见的眼部表现 (91.1%),其次是视网膜血管炎 (37.8%).
- 眼部并发症发生在51.1%的眼睛中,与早期发病和更多的复发有关.
- 人类白细胞抗原 (HLA) -B51阳性预测了较差的最终视力敏度,初始视力敏度预测了失明.
结论:
- 在jBD中,眼部的参与是常见的,并可能导致显著的视力损伤.
- 了解这些表现和相关因素对于临床管理至关重要.
- 需要进一步的研究来改善这种危及视力的疾病的结果.
相关概念视频
Glaucoma: Overview
565
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
565
Open Angle Glaucoma: Treatment
440
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
440
Angle Closure Glaucoma: Treatment
485
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
485


