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Updated: Jun 29, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

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针对CD8+T细胞的IL2促进了强大的T细胞反应和强大的抗瘤免疫力

Kelly D Moynihan1, Manu P Kumar1, Hussein Sultan2

  • 1Asher Biotherapeutics, Inc., South San Francisco, California.

Cancer discovery
|April 2, 2024
PubMed
概括

向 CD8+ T 细胞准介素-2 (IL2) 增强了抗瘤活性,同时降低了毒性. 这种新的方法,以AB248为例,可以选择性地扩展CD8+T细胞,提高癌症治疗潜力.

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