相关实验视频

Updated: Jun 29, 2025

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
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Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

Published on: May 10, 2019

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BAI1将AMPA受体定位在耳 afferent后突触密度,对于听力至关重要

Adam J Carlton1, Jing-Yi Jeng1, Fiorella C Grandi2

  • 1School of Biosciences, University of Sheffield, Sheffield S10 2TN, UK.

Cell reports
|April 2, 2024
PubMed
概括

脑特异性血管生成抑制剂1 (BAI1) 对听力至关重要. BAI1 缺陷阻止AMPA受体在突触处聚合,损害从内毛细胞到螺旋性质神经元的声音信息传输.

关键词:
科普:神经科学是什么意思在NDMA受体中,NDMA受体有关纤维的纤维.甲状腺 (cochlea) 是一种发展发展发展发展发展.葡萄糖酸盐受体的受体头发细胞是指毛细胞.听力损失 听力损失是什么后突触密度 后突触密度带状突触可以通过带状突触.

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The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
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Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
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Hair Cells01:22

Hair Cells

Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
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When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
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Anatomy of the Ear

Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
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