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高剂量异化物缺乏早期抗异化物耐药性结核病的早期杀菌活性,介于katG突变:一项随机的II期临床试验

Kamunkhwala Gausi1, Elisa H Ignatius2, Veronique De Jager3

  • 1Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

American journal of respiratory and critical care medicine
|April 2, 2024
PubMed
概括

高剂量异化对具有katG突变的结核病菌株具有最小的早期杀菌活性. 这表明大多数患者治疗多药耐药结核病的疗效有限,即使剂量更高.

关键词:
早期的细菌杀菌活性.异化物耐药性 异化物耐药性这是一种katG突变.第二阶段临床试验.结核病是一种肺结核病.

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