在接受非心脏手术的患者中,心率变化和外科期间神经认知障碍之间的相关性:一项回顾性队列研究
Xiaoye Liu1,2, Hengjun Wan1,2, Huide Wang3
1Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan Province, China.
PloS one
|April 2, 2024
概括
低的手术前心率变化 (HRV) 是非心脏手术患者手术后神经认知障碍 (PND) 和ICU入院的重要独立风险因素. 低HRV的患者经历了更高的PND率和更长的住院时间.
科学领域:
- 麻醉学 麻醉学
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 神经学 神经学
背景情况:
- 越来越多的老年人群需要注意手术后的结果.
- 经手术的神经认知障碍 (PND) 在非心脏手术中越来越令人担忧.
- 手术前心率变化 (HRV) 和PND之间的关系仍未得到充分研究.
研究的目的:
- 在接受非心脏手术的患者中调查手术前HRV和PND之间的相关性.
- 探索HRV与术后重症监护室 (ICU) 入院和住院的关联.
主要方法:
- 对687名接受24小时动态心电图的住院患者的回顾性分析.
- 患者被分为高和低HRV组.
- 多变量后勤回归和子组分析,以确定PND和ICU入院的独立风险因素.
主要成果:
- 在36.7%的患者中观察到低HRV; PND发生率为7.6%.
- 低HRV组显示PND率显著更高 (11.8%与5.2%相比),ICU转移增加 (15.9%与9.3%相比),住院时间更长.
- 降低了独立预测的低HRV PND (AOR=2.095) 和ICU入院 (AOR=1.925).
- 纳米图包括年龄和HRV,证明了预测能力 (C指数=0.696).
结论:
- 在非心脏外科手术中,低的手术前HRV是PND和术后ICU转移的独立风险因素.
- 长时间住院与低HRV有关.
- 对PND的预测模型可以帮助高风险患者进行早期干预.
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