以色列急性乳腺炎的新兴临床特征:一个基于登记册的队列
Orit Samuel1,2,3,4, Walid Saliba2,5, Nili Stein5
1From the Department of Otolaryngology-Head and Neck Surgery, Carmel Medical Center.
The Pediatric infectious disease journal
|April 2, 2024
概括
儿童急性乳腺炎 (AM) 在两岁以下的儿童中呈现不同,并发症与特定细菌和炎症标志物升高有关. 微生物学在研究期间发生了转变,尽管进行了肺炎球菌疫苗接种.
科学领域:
- 儿童传染病 儿童传染病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- 急性乳腺炎 (AM) 是一种严重的儿科感染,有可能导致严重的并发症.
- 了解AM的特征对于及时诊断和治疗年轻患者至关重要.
研究的目的:
- 描述10年来急性乳腺炎的表现,症状,迹象,并发症和治疗方法.
- 为了确定与儿童AM并发症相关的因素.
主要方法:
- 一项基于人口的队列研究,对2008-2018年间被诊断患有AM的18岁以下患者进行.
- 分析临床数据,疫苗接种情况,实验室结果,微生物学,成像和治疗干预措施.
主要成果:
- 1189名患者被诊断患有AM;较小的儿童 (<2岁) 呈现出更多的症状和更高的炎症标志物.
- 在20.8% (局部) 和6.5% (内) 发生并发症,与白细胞数量升高,C反应蛋白和Fusobacterium necrophorum相关.
- 在研究期间观察到微生物学的显著转变,Streptococcus pneumoniae减少和A组Streptococcus增加.
结论:
- 在两岁以下的儿童中,AM的表现有所不同.
- 炎症标志物和特定的微生物学 (例如,Fusobacterium necrophorum) 与AM并发症有关,为管理决策提供了信息.
- 该研究强调了肺炎球菌疫苗时代对AM微生物学的重大变化.
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