儿童和青少年的皮肤和软组织动因菌病
Salih Demirhan1, Erika Orner2, Wendy Szymczak2
1From the Division of Infectious Diseases, Department of Pediatrics, Children Hospital at Montefiore and Albert Einstein College of Medicine.
The Pediatric infectious disease journal
|April 2, 2024
概括
儿科行动性菌,一种皮肤感染,经常复发. 诸如培养中的单个细菌,高BMI和先前等因素会增加儿童和青少年的复发风险. 对于这种难以治疗的感染,需要改善提供者教育.
科学领域:
- 医学微生物学 医学微生物学
- 儿童传染病 儿童传染病
- 皮肤病学 皮肤病学
背景情况:
- 有限的研究存在于儿科行为性菌病,主要是从病例报告.
- 这项研究通过检查儿童和青少年的皮肤和软组织动态菌病来解决数据的稀缺问题.
研究的目的:
- 在儿科患者中表征皮肤和软组织动态菌症.
- 确定与青少年和儿童中这种感染复发相关的危险因素.
主要方法:
- 对21岁以下的患者进行了回顾性队列研究,在无菌培养中进行了Actinomyces生长.
- 包括从2019年1月到2022年12月至少有1年的随访数据的患者.
- 分析了临床特征,治疗和复发率.
主要成果:
- 包括104名儿科患者;68.3%是女性,平均年龄为19岁.
- 病例复发记录在三分之一的患者身上,复发的中位时间为10个月.
- 复发的重大风险因素包括单菌生长 (OR:3.4),BMI>25 (OR:2.7),以及同一区域的先前 (OR:4.6).
结论:
- 在儿科皮肤和软组织感染,特别是复发病例中,应考虑Actinomyces物种.
- 观察到低于最佳的抗生素使用率和低的传染病咨询率.
- 调查结果强调需要更新提供者对管理这种具有挑战性的感染及其复发因素的知识.
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