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Updated: Jun 29, 2025

Author Spotlight: A Selective Luciferase-Based Assay for Monitoring ATG4B 27 Activity in Cells
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通过自胞体降解剂向EGFR降解

ZhongFeng Zhu1, Jiaying Li1, Shujun Shen1

  • 1State Key Laboratory of Bioactive Molecules and Druggability Assessment, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development, Ministry of Education (MoE) of the People's Republic of China, Guangzhou City Key Laboratory of Precision Chemical Drug Development, College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou, 510632, China.

European journal of medicinal chemistry
|April 2, 2024
PubMed
概括

新的自细胞结合化合物 (ATTEC) 在非小细胞肺癌 (NSCLC) 细胞中有效降解表皮生长因子受体 (EGFR). 这种方法提供了一种新的策略,以克服NSCLC治疗中的耐药性.

关键词:
这就是ATTECs的意义.降解器降解器降解器欧洲农业基金会 (EGFR) 是一个基金.在 LC3B 里面,你会看到 LC3B.在NSCLCLC中,我们可以看到.

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