丹麦老年人肺癌 - - 一项基于人口的综合性队列研究
Niels Lyhne Christensen1, Anja Gouliaev2, Sean McPhail3
1Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Research Unit for General Practice, Aarhus, Denmark.
Lung cancer (Amsterdam, Netherlands)
|April 2, 2024
概括
老年肺癌患者,特别是80岁及以上的患者,接受的诊断测试和治疗较少. 这一年龄组面临着明显更高的早期死亡风险,突出显示了肺癌护理方面的差异.
科学领域:
- 在瘤学瘤学.
- 老年医学 老年医学
- 公共卫生 公共卫生
背景情况:
- 肺癌主要影响老年人,在丹麦,诊断时的平均年龄为73岁.
- 在临床试验和肺癌查研究中,老年人往往没有得到充分的代表.
- 了解老年肺癌患者面临的具体挑战对于改善护理至关重要.
研究的目的:
- 为了描述丹麦的老年肺癌患者 (≥80岁).
- 在这个人口群体中探索诊断强度和治疗模式.
- 分析老年人与年轻肺癌患者的生存结果.
主要方法:
- 使用来自丹麦癌症登记处和丹麦肺癌登记处 (2014-2017) 的数据进行了回顾性研究.
- 包括17835名肺癌患者,重点关注2871名80岁或以上的患者.
- 将患者数据与丹麦统计局的信息联系起来,以便进行全面分析.
主要成果:
- 与年轻患者相比,80岁以上的患者的肺活检率 (47%vs53%) 和中腔手术率 (34%vs26%) 较低.
- 较少的老年患者接受治疗登记 (60% vs 85%) 或治疗治疗 (23% vs 42%).
- 老年患者 (≥80岁) 在诊断后12个月内死亡的几率高出2.1倍.
结论:
- 80岁及以上的肺癌患者的诊断强度较低.
- 晚年与手术或治疗意图治疗的可能性降低有关.
- 80岁以上的年龄与肺癌所有治疗组的不良预后有关.
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