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相关概念视频

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Phylogenetic Trees03:21

Phylogenetic Trees

45.3K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
45.3K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

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The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.1K
Phylogeny01:23

Phylogeny

44.0K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
44.0K
The Tree of Life - Bacteria, Archaea, Eukaryotes02:40

The Tree of Life - Bacteria, Archaea, Eukaryotes

32.4K
The “tree of life” describes the evolution of life and the evolutionary relationships between organisms. The root of the tree is the common ancestor to all life on Earth. All other species radiate from this point, much like the branches of a tree. The numerous tips of these branches on the tree of life represent every living, or extant, species. Extinct species, which are species that no longer exist, can be found towards the center of the tree. Currently, these organisms, both...
32.4K
Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

27.8K
Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
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相关实验视频

Updated: Jun 29, 2025

A Practical Guide to Phylogenetics for Nonexperts
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A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

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机器学习在遗传学中的应用.

Yu K Mo1, Matthew W Hahn2, Megan L Smith3

  • 1Department of Computer Science, Indiana University, Bloomington, IN 47405, USA.

Molecular phylogenetics and evolution
|April 2, 2024
PubMed
概括

机器学习 (ML) 通过分析树建和模型选择的模拟数据来帮助遗传学推断. 克服目前的障碍将增强ML.

科学领域:

  • 计算生物学 计算生物学
  • 进化生物学 进化生物学
  • 生物信息学是一种生物信息学.

背景情况:

  • 机器学习 (ML) 越来越多地被用于遗传学推断.
  • 监督的ML方法使用模拟数据来执行诸如树拓推断,分支长度估计和替代模型选择等任务.
  • ML也适用于下游的遗传学分析,包括内进和多样化.

研究的目的:

  • 审查监督机器学习方法在基因推理中的应用.
  • 确定阻碍ML在遗传学中充分发挥潜力的障碍.
  • 建议未来的方向,以推进ML在这个领域.

主要方法:

  • 审查现有的文学监督机器学习在家族遗传学.
  • 分析如何应用ML方法来推断树木拓,分支长度和替代模型.
  • 讨论现有ML应用中的挑战和局限性.

主要成果:

  • 监督的ML在各种遗传学推断任务中表现有前途.
  • 目前有几个障碍限制了监督ML在遗传学中的广泛采用和有效性.
  • 审查强调了ML方法正在成功实施的特定领域.

结论:

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相关实验视频

Last Updated: Jun 29, 2025

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.3K
Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

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Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
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Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

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  • 尽管存在挑战,但监督的ML具有很大的潜力,可以推进遗传学推断.
  • 通过改进网络设计和数据编码来解决当前的障碍至关重要.
  • 未来的ML应用预计将更好地适应挑战传统遗传学方法的复杂进化过程.