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Updated: Jun 29, 2025

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry
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用Gβγ媒介激活氏体3-酶 γ 的分子基础

Chun-Liang Chen1,2, Ramizah Syahirah1, Sandeep K Ravala1,2

  • 1Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.

Nature structural & molecular biology
|April 2, 2024
PubMed
概括

由Gβγ激活的酸酸3-激酶 (PI3Kγ) 对细胞运动和癌症扩散至关重要. 结构研究揭示了两个调节PI3Kγ活动和膜招募的Gβγ结合位点.

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