在服用抗凝剂的患者中,经过牙膜外科手术后出现术后出血的风险:使用共同数据模型的队列研究
Joo-Yeon Lee1, Seung-Hyun Park1, Da-Mi Kim1
1Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Scientific reports
|April 2, 2024
概括
抗凝剂类型和特定的牙气管外科手术,如骨移植的提取,会增加出血风险. 仔细考虑抗凝剂的使用对于这些程序期间的患者安全至关重要.
科学领域:
- 口腔和牙面部外科手术
- 心脏病学 心脏病学
- 血液学 血液学 血液学
背景情况:
- 手术后出血是接受牙气管外科手术的患者,特别是接受抗凝药治疗的患者的重大问题.
- 在接受牙科手术的患者中,管理抗凝血需要仔细评估风险,以平衡出血并发症和血栓栓塞事件.
研究的目的:
- 在接受牙气囊外科手术的服用抗凝血剂的患者中识别术后出血的危险因素.
- 为了比较继续服用抗凝剂的患者和停止服用的患者之间的出血率.
主要方法:
- 在537名接受抗凝药治疗的患者中进行了回顾性研究,这些患者接受了牙气管外科手术 (牙周,拔牙,植入物手术).
- 患者被分为抗凝固剂维持组和停止组.
- 分析与患者相关的因素 (全身性疾病,抗凝剂类型) 和与治疗相关的因素 (外科手术,静血方法).
主要成果:
- 整体手术后出血率为6.5% (35/537),维持组 (8.6%) 的出血率高于停止组 (4.8%).
- 出血的重要危险因素包括抗凝剂类型,用骨移植拔牙和植入器手术类型.
- 在维持组中,心房动和维生素K抑制剂与明显更高的出血风险有关.
结论:
- 在dentoalveolar手术期间继续服用抗凝药的决定应该是个性化的.
- 手术因素,如用骨移植进行提取,多次植入和大门干涉等,需要仔细的抗凝剂管理.
- 进一步的研究可能会完善在这种患者群体中管理抗凝血的协议.
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