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Updated: Jun 29, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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USP26通过抑制PRKN介导的线粒细胞衰变促进结直肠癌瘤发生

Qi Wu1, Zhihong Wang1, Siqi Chen1

  • 1GI Cancer Research Institute, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, China.

Oncogene
|April 2, 2024
PubMed
概括

乌比基因特异性酶26 (USP26) 通过二氧化基因和抑制帕金酶 (PRKN) 来促进结直肠癌 (CRC). 抑制USP26可能通过恢复PRKNN提供新的CRC疗法.

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