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在已发展的品种中,基因组证据表明人为介导的内进杂交和选择

Heng Du¹, Zhen Liu¹, Shi-Yu Lu¹

¹State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University (West District), No.2 Yuanmingyuan West Road, 100193, Beijing, China.

|April 2, 2024

概括

北京黑猪表现出侵入性的杂交起源,人类介导的侵入性塑造了它们的基因组架构. 这项研究揭示了选择信号,并确定了影响这种发达品种肉质特征的关键基因.

科学领域:

基因组学就是基因组学.
动物育种动物育种
人口遗传学人口遗传学

背景情况:

猪 (Sus Scrofa) 是重要的牲畜,具有明显的欧洲和亚洲品种特征.
现代育种广泛利用了欧亚种类,但发达品种的基因组结构仍未得到充分研究.
在繁殖期间,人类对猪基因组的影响尚未完全被理解.

研究的目的:

为了研究北京黑猪的基因组架构和起源,这是一个本地开发的亚洲品种.
在北京黑猪基因组中识别人类介导的侵入和选择特征.
发现与肉质特征相关的候选基因.

主要方法:

对178只北京黑猪及其祖先的全基因组分析.
识别内进的基因组区域和选择信号.
对肉质特征进行全基因组关联研究.

主要成果:

北京黑猪表现出内向的混合起源与不一致的基因和物种树.
检测到来自亚洲祖先的显著内进,以及欧洲遗传关系.
确定了554个内进区域 (63.30 Mb) 和7.77%的选择区域,其中的基因与肉质,生育能力和抗病能力有关.
DNAJC6和RUFY4被确定为肌肉内脂肪,pH和柔软性的候选基因.

结论:

人类介导的内进显著塑造了发达猪品种的基因组结构.
了解这些基因组模式对于分析现代动物育种中的品种起源和选择至关重要.
鉴定出来的基因提供了关于北京黑猪肉质量的遗传基础的见解.

关键词:

发达的品种种类型.遗传结构遗传结构内进侵权侵权是一种内进.现代育种是现代的育种.猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪选择选择选择选择

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