减肥后怀孕与维生素K1缺乏有关,这是一项病例对照研究
Brit Torunn Bechensteen1,2, Cindhya Sithiravel3, Ellen Marie Strøm-Roum4
1Department of Endocrinology, Akershus University Hospital HF, Lørenskog, Norway.
BMC pregnancy and childbirth
|April 2, 2024
概括
减肥手术后的怀孕,特别是胃绕道手术,与较低的维生素K1水平有关. 这增加了维生素K1缺乏的风险,可能会影响母亲和孩子.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 手术研究的研究.
背景情况:
- 孕产妇的肥胖对怀孕的结果构成风险.
- 减肥手术可以改善生育能力,并减少某些妊娠并发症.
- 腹部外科手术后的最佳营养监测仍然不清楚.
研究的目的:
- 评估减肥手术对怀孕期间微量营养素水平的影响.
- 为了比较胃绕道术和袖子胃切除术患者之间的微量营养素概况.
- 为了确定与 Post-bariatric 怀孕相关的风险.
主要方法:
- 一项前性病例控制研究,涉及204名孕妇.
- 包括59名先前接受过减肥手术的女性和145名对照女性.
- 血液样本和临床问卷收集在怀孕20周左右.
主要成果:
- 与对照组相比,腹部外科手术的妇女怀孕前的BMI较高,但体重增加和妊娠糖尿病的发病率相似.
- 在减肥后的怀孕中观察到显著较低的维生素K1水平.
- 胃绕道手术与维生素K1缺乏的风险高于袖子胃切除术.
结论:
- 减肥后怀孕与维生素K1水平降低和缺乏症风险增加有关.
- 与袖子胃切除相比,胃绕道手术对维生素K1缺乏的风险更大.
- 在这些怀孕中,维生素K1缺乏可能导致低凝血状态,需要进一步调查.
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